What antidepressants help with hot flashes? Antidepressants. A low-dose form of paroxetine (Brisdelle) is the only nonhormone treatment for hot flashes approved by the Food and Drug Administration. Other antidepressants that have been used to treat hot flashes include: Venlafaxine (Effexor XR, Pristiq) What is the best drug for menopause? Treatments may include: Hormone therapy. Estrogen therapy is the most effective treatment option for relieving menopausal hot flashes. Vaginal estrogen. Low-dose antidepressants. Gabapentin (Neurontin, Gralise, others). Clonidine (Catapres, Kapvay, others). Medications to prevent or treat osteoporosis. Does the menopause make you forgetful? One major change to the body that may cause normal forgetfulness during menopause is a reduction in the body's hormone levels. Estrogen is one major hormone that can impact memory before or during menopause. This can cause occasional lapses in brain function, resulting in short-term memory issues.
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